Ensuring that as artificial intelligence advances, it remains beneficial and aligned with human values.

Safeguarding life against biological risks, from pandemic prevention and preparedness to mitigating the potential misuse of biotechnology.

Identifying and prioritizing the most effective interventions to alleviate poverty, reduce suffering, and maximize well-being on a global scale.

Thinking beyond the immediate horizon to anticipate and address the challenges and opportunities that will shape humanity's trajectory.

Analyzing complex interconnected threats, such as nuclear war, climate change, and emerging technologies, while enhancing international stability and resilience.